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  • 產(chǎn)品名稱：ABL1抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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ABL1抗原（重組蛋白）也迎來了抗體銷售的黃金期了，誰能在這個時(shí)刻掌握好客戶資源，誰就能獲得良好的口碑，我司董事會經(jīng)過深思熟慮，在反饋客戶問題方面，我們時(shí)時(shí)跟蹤及服務(wù)，再次，就是在產(chǎn)品優(yōu)惠方面，買就送的優(yōu)惠活動。
詳情介紹：



中文名稱： ABL1抗原（重組蛋白）

英文名稱： ABL1 Antigen (Recombinant Protein)

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human ABL1

技術(shù)規(guī)格

Full name:

c-abl oncogene 1, non-receptor tyrosine kinase

Synonyms:

ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl

Swissprot:

P00519

Gene Accession:

BC117451

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.







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