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  • 產(chǎn)品名稱：BCL2A1抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
BCL2A1抗原（重組蛋白）打造了一支訓練有素的技術團隊，為抗體產(chǎn)品質量提供了強有力的保障，一直致力于研發(fā)生產(chǎn)高質量的科研試劑，為生命科學提供**的蛋白檢測相關產(chǎn)品，先進的實驗設備，強大的技術力量，誠信的服務態(tài)度是您實驗成果的保障！
詳情介紹：


中文名稱： BCL2A1抗原（重組蛋白）

英文名稱： BCL2A1 Antigen (Recombinant Protein)

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1-175 amino acids of human BCL2A1

技術規(guī)格

Full name:

BCL2-related protein A1

Synonyms:

GRS; BFL1; ACC-1; ACC-2; HBPA1; BCL2L5

Swissprot:

Q16548

Gene Accession:

BC016281

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.





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